The violent forces generated by the strong paraspinal muscles during generalized tonic-clonic seizures are known to be associated with numerous musculoskeletal injuries and mostly with vertebral fractures. Vertebral fractures following epileptic seizures are typically a single compression fracture, mostly occurring in the midthoracic region and usually without resultant neurological deficit. Despite the relative frequency of single level vertebral compression fractures complicating seizures, less frequently two or three adjacent vertebrae might be affected by the seizure. However, non-contiguous multiple compression fractures after grand mal epilepsy have been not reported previously.

Herein, a 40-year-old male experienced witnessed grand mal seizure resulting in 3-level compression fracture at 3 levels at thoracic spine and two levels at thoracolumbar region the patient was managed conservatively with an appropriate orthosis. The current case might be the first seizure induced non-contiguous multilevel compression fractures reported in the literature.