Since the introduction of da Vinci robotic system in the 1990s, robot-assisted techniques have been applied to a wide variety of surgical specialties such as urology, obstetrics and gynecology, cardiac surgery, head and neck surgery, and more recently, spine surgery. Here we describe a technical description of the clinical application of robotic surgery to a 22-year-old female with a 7 x 6.2 x 5.8 cm presacral schwannoma originating from the right S2 neural foramen as well as a review of the treatment of presacral tumors and the current evidence supporting the use of robot-assisted surgical techniques.